BDBM427762 US10544143, Example 195::US10544143, Example 199

SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(nc2c1C(C)C)C1CCC(CC1)N1CCCC1

InChI Key InChIKey=JDGZEKNWRDRRRG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 427762   

TargetToll-like receptor 8(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM427762(US10544143, Example 195 | US10544143, Example 199)
Affinity DataIC50:  4.30nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM427762(US10544143, Example 195 | US10544143, Example 199)
Affinity DataIC50:  6.40nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent